This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia. It addresses 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions.
New recommendations are made for the choice and number of drugs in a regimen, the duration of intensive and continuation phases, and the role of injectable drugs for MDR-TB. On the basis of these recommendations, an effective all-oral regimen for MDR-TB can be assembled. Recommendations are also provided on the role of surgery in treatment of MDR-TB and for treatment of contacts exposed to MDR-TB and treatment of isoniazid-resistant TB.
Hospital-acquired pneumonia (HAP) is an infection of the pulmonary parenchyma caused by pathogens that are present in hospital settings. Ventilator-associated pneumonia (VAP) develops in intensive care unit (ICU) patients who have been mechanically ventilated for at least 48 h.These guidelines cover the diagnosis, treatment and prevention of these conditions.
International Standards for Tuberculosis Care defines the essential level of care for managing patients who have or are presumed to have tuberculosis, or are at increased risk of developing the disease.
Chronic pulmonary aspergillosis (CPA) is an uncommon and problematic pulmonary disease, complicating many other respiratory disorders, thought to affect ∼240 000 people in Europe. The most common form of CPA is chronic cavitary pulmonary aspergillosis which untreated may progress to chronic fibrosing pulmonary aspergillosis. Less common manifestations include: Aspergillus nodule and single aspergilloma. These guidelines cover the clinical, radiological and microbiological managment of these conditions.
Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (TB disease) or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]).These guidelines provide the basis for rational decisions in the diagnosis of tuberculosis.
This guideline provides recommendations on the clinical and public health management of tuberculosis in children and adults in settings in which mycobacterial cultures, molecular and phenotypic drug susceptibility tests, and radiographic studies, among other diagnostic tools, are available on a routine basis.
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. These international guidelines provide 93 statements on early management and resuscitation of patients with sepsis or septic shock.
The BTS guideline for CAP in adults was published in 2009. NICE published guideline 191 on Pneumonia in December 2014. Recognising differences in the scopes of the two guidelines, this annotated edition of the BTS guideline indicates where recommendations remain valid, and where overlaps exist.
UK National Institute for Health and Clinical Excellence evidence based guidelines on Pneumonia; Diagnosis and management of community and hospital acquired pneumonia in adults.
European Respiratory Society (ERS) and European Society of Clinical Microbiology and Infectious Diseases evidence-based recommendations for the most common management questions occurring in routine clinical practice in the management of adult patients with LRTI.
British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011
An Official ATS Workshop Report: Emerging Issues and Current Controversies in HIV-Associated Pulmonary Diseases
An Official American Thoracic Society Statement: Treatment of Fungal Infections in Adult Pulmonary and Critical Care Patients
The Management of Community-Acquired Pneumonia in Infants and Children Older Than 3 Months of Age: Clinical Practice Guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America
World Health Organisation (WHO) guidelines for the pharmacological management of pandemic Influenza A (H1N1) other Influenza Viruses: Recommendations
British Thoracic Society Guidelines for the management of community acquired pneumonia in adults
UK National Institute of Health and Clinical Excellence (NICE) recommends Oseltamivir and Zanamivir for the treatment of influenza in adults and children if influenza virus A or B is circulating, the person is in an ‘at-risk’ group, the person presents with an influenza-like illness and can start treatment within 48 hours (or within 36 hours for zanamivir treatment in children) of the onset of symptoms.
Defining, treating and preventing hospital acquired pneumonia: European perspective produced by the European Respiratory Society (ERS), European Society of Clinical Microbiology and Infectious Diseases and the European Society of Intensive Care Medicine.
World Health Organisation revised guidance on the clinical management of human infection with pandemic (H1N1)