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Category Archives: Journal Club

Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19

Posted on May 14, 2020 by Lunglead

Ivan Fan-Ngai Hung, Kwok-Cheung Lung, Eugene Yuk-Keung Tso et al The Lancet     DOI: https://doi.org/10.1016/S0140-6736(20)31042-4 A multicentre, prospective, open-label, randomised, phase 2 trial in adults with COVID-19 who were admitted Continue Reading →

Posted in Journal Club

Pitolisant for Daytime Sleepiness in Patients with Obstructive Sleep Apnea Who Refuse Continuous Positive Airway Pressure Treatment. A Randomized Trial

Posted on May 14, 2020 by Lunglead

Yves Dauvilliers, Johan Verbraecken , Markku Partinen et al AJRCCM 2020 201 (9)  doi.org/10.1164/rccm.201907-1284OC The aim of this study was to evaluate the efficacy and safety of pitolisant, a selective Continue Reading →

Posted in Journal Club

The impact of sleep disorders on risk and outcome of stroke

Posted on May 14, 2020 by Lunglead

Claudio L.A. Bassetti, Winfried Randerath, Luca Vignatelli et al European Respiratory Journal 2020 55: 1901104; DOI: 10.1183/13993003.01104-2019 This European Academy of Neurology (EAN), European Respiratory Society (ERS), ESRS, and the Continue Reading →

Posted in Journal Club

Chronic obstructive pulmonary disease and lung cancer incidence in never smokers: a cohort study

Posted on May 14, 2020 by Lunglead

Hye Yun Park et al. Thorax. Published Online First: 02 April 2020. doi: 10.1136/thoraxjnl-2019-213732 The aim of this study was to estimate the risk of lung cancer incidence in never smokers with COPD, Continue Reading →

Posted in Journal Club

NEW GUIDELINE: TB preventative treatment

Posted on May 14, 2020 by Lunglead

WHO Updated guideline on tuberculosis preventive treatment contains new recommendations and covers critical steps in programmatic management that follow the cascade of preventive care. The main changes include conditional recommendations Continue Reading →

Posted in Journal Club

NEW GUIDELINE: Withdrawal of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease

Posted on May 14, 2020 by Lunglead

James D. Chalmers, Irena F. Laska, Frits M. E. Franssen et al  European Respiratory Journal 2020 55 (5)   DOI: 10.1183/13993003.00351-2020 Inhaled corticosteroids (ICS) combined with bronchodilators can reduce the frequency of exacerbations in some patients with chronic Continue Reading →

Posted in Journal Club

NEW GUIDELINE: Pharmacologic Management of Chronic Obstructive Pulmonary Disease

Posted on May 14, 2020 by Lunglead

Linda Nici, Manoj J. Mammen, Edward Charbek et al Am J Respir Crit Care Med Vol 201, Iss 9, pp e56–e69, May 1, 2020 This guideline form the ATS Provides Continue Reading →

Posted in Journal Club

NEW GUIDELINE: COVID-19 rapid guideline: antibiotics for pneumonia in adults in hospital

Posted on May 14, 2020 by Lunglead

NICE guideline on antibiotics for pneumonia. The aim is to ensure the best antibiotic management of suspected or confirmed bacterial pneumonia in adults in hospital during the COVID‑19 pandemic. This Continue Reading →

Posted in Journal Club

Prevalence, Severity and Mortality associated with COPD and Smoking in patients with COVID-19: A Rapid Systematic Review and Meta-Analysis.

Posted on May 14, 2020 by Lunglead

Alqahtani JS, Oyelade T, Aldhahir AM et al. PLoS ONE 2020 15(5): e0233147. https://doi.org/10.1371/journal.pone.0233147 There is a debate about the influence of smoking on morbidity and mortality associated with infection Continue Reading →

Posted in Journal Club

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